Chronic stress affects the brain in several powerful ways: Stress raises cortisol, which damages brain cells Long-term elevated cortisol (the stress hormone) can shrink the hippocampus, the part of the brain responsible for memory and learning. Stress increases inflammation Chronic inflammation accelerates brain ageing and is linked to cognitive decline. Stress worsens other dementia risk factors Stress doesn’t work alone — it drives behaviours and conditions that directly increase dementia risk
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